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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec79739e472280ee9a5052d7044bf790a2200a6f9f23c76a18620d7122978741' 
  AND token = 'kD81M3RF4LxeTT+RO9aL5iGT+fcclU63PppXEHRWdIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}