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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8873159edd00cb6e870d909e1590e03c835ff2847f18f89179ceebb4981fbb91' 
  AND token = 'tWyAk1ueOX2raZDrkDhS7TihlmzoynAdwcq4MEjXOTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}