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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8d390e90044e514c422723d2b6d6580e2f06cb9a11283c1aa601b80d847a861' 
  AND token = 'lxbdyJRBVYIHGqlj4O7S//0cRsBR3r1vtsGcpMXkVoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}