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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e161ab0db208da4e9d9700228f5c866bd2bc139ed5433e5bb795e60c6988d005' 
  AND token = '1tiNk4OjUimz+wKHfL3w+vu36sKRrjz8XDpU2iLGTKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}