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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '226f367709986654e42db855277acb51f537de1d2ca2d19480b630ffa7f34a15' 
  AND token = 'P2oRlVNuCWC2sBvA8wn2oQEX6shycJYKcpaCRdiPGIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}