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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a9b86a68d8c223fb8edffb1905fff609384ab758e6c19c3fb364119ae17c64' 
  AND token = '6VBsr0CwP2Yaonp6VJyBbNLSSIPojg989UQd1ebpT9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}