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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a7eca1565ee172db35db54f0479ee9186ea712f6ec3180ce934ace1d2648786' 
  AND token = 'DS6O9+B1umUSveT+F0JGvC8Ef4mgB5AFUHlvf0Ge61k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}