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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e97897aeee97e6a93c67f7425479f4646091a7fc691a54c9c08282a2db6ed221' 
  AND token = '/zm0UO4G7WoW9NOgZc3ucyQXZ4tJ/pD4vB+oL9FGcxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}