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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1115fcea3e122689414a4a0cec2029524be1f84b2c9c80f71ed2310e0202dd86' 
  AND token = 'MW3VdOh3+M2YL9CZLm8SRs0RceBKkaK3Zu+aWtaqVuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}