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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a7090b264768b91a64ae89a3db24b65b92fce6a7b70629f882b010801e14907' 
  AND token = 'PIr/KiQQDSFyT1JqyzYRWHeD5qWMKbRNBobsQpZyMkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}