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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13c1ad26a099b8aceca2aec881d3fe0e37e68bdac86b2bba4fda399eb9b65291' 
  AND token = 'O6vTAyGoHG5zPLpHd8VaLERiGU3ZF/5pOpiM3uI92b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}