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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '591b12eac803a98dd45d21617e38af947a5759eca45d32d58ffd2a4b381b42bc' 
  AND token = 'UCpAJed9/uppUJDOOzuC32j/KWgPiOyHXUtFRx9u7Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}