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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380a3cf7eccfef3fc900600092d1d9d44971cc62d698fc939c7d7a2a275b088f' 
  AND token = '4b95dGQL4DFTk7+pLgY7FWUqgh/P+GJEiQ98qLGtWpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}