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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1da7f83199c0fd026e38a449fe86cf2985247330174975983e06dc1d378c8ecc' 
  AND token = 'l4yTsuUcR2LK1S8EL4jI1sCELeVZo+i6IAoKAO2gPwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}