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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d1457cf2baef697c9f6e93c0192e5193c6d328f570d9acdc8a479607736e733' 
  AND token = 'iUNjTVcu1ZTJxZd4C9sMHwQVhSbQT3hfo9/iiOh2/fU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}