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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16b0757ece76c1b80cca017b7939259fed43bdac80cb821ffe9413c36e2fd8bb' 
  AND token = 'wii1KtiXEAdx7p4X7eNv+UnuUJCce2KocZ1WiSDr0n0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}