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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c8485796e85c6c658a32364b745c4280102b0b3a491fc121021a1b0ab6d59cb' 
  AND token = 'qYtJHqAu+FkeLD07daMJjSEQ1VOg+SapiWHQz2WPzFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}