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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecd29d48f61c5f11f5f94045bf0d68a5655c944c686b7ed9f608f99b3fd5d341' 
  AND token = 'wtsBq65E4U5ZloCsoUdhADW/ZM40zG57HtdQM6Yold0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}