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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6762bd98820bc1fc35853ba08866650e44b456738e893205824c840bca1dcfa8' 
  AND token = '2z5JEVxo/9KE2mNk2fakX35Lg2ChhPLnKMsvBxIuK7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}