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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb2739d94ccd0c7d0f611cbac64fee5a10cf5a0fbcb21295f510fc63e933b028' 
  AND token = 'ZcOKp6bkwnNBvqlUfTKVq1y6lH8Q6/7yP42htj/AQio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}