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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '301d7ab61a1c15ea68adcd8cb0bc8fbdef6a6362101b6abd8717091feb0bd8db' 
  AND token = '4VisaHwkp7nXbGsl/PTuorae2iWBBhJ5KhDbqR82lXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}