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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eed1f8d48641621a1010686356b13bc9c7f841a9ad1164151603936f41467dd' 
  AND token = 'QbC0QZueJfepQTOO5j/dC+k41PydFaZ16bMLEMW2wGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}