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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'deed7f017c2729ef3b4285a993351fc4d427910eeb984724cdc5e94008449ed4' 
  AND token = 'zfBuPY1llQTWqx8lWDchs+6TL2/T8/QLLMQnbPXyzR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}