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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6114a99bf6133403829a321a302049a17a5448fa1b9f616954f5090e8736d9ad' 
  AND token = 'rEf0bL0Osp1rm1KaKiny1OAHwzNhLCb7jnWEJ7WR0Vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00075

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}