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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e7c38fa4c0844eee61b3c3978b04a1dd94a159133240845f486f3213259200b' 
  AND token = 'kZ4Poqbze8y5RlZ5ZXBSEruStHhiSOtKmO3slwUarcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}