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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2c549955204c8fa518b4c6d25322c0139bdc2a6786072a07e7b1824e0cd8c6f' 
  AND token = 'eeMVB0LyRuiT2AVpRMJnSANUZu/ZDFOj8llVOKb3iyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}