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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc12b7a1283fbae0badeafb97f17f319001d5362e98a6946112dae9172b46900' 
  AND token = '046X7vIvBDFH7453RByJIMeHE6B3jAMWNSmq4X5PSjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}