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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff49030cc96a65b2de83a2036735610ae3d4a1d4c963dceb44e8c87bd023da3' 
  AND token = 'mr8V812BxqEH4rbzely+A5leCbB8KLVYDbU/TOMQkRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}