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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b11d8ff175969bb0e465e2948cbfdf37b971f009f55bf9e84e904e21ba96009' 
  AND token = 'goHUJlexLz9ZTMDgq4Em1c2EYMdZhlv4Wn2Yut+7b1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}