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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec06c49a85d62070d38729d280f8726d3227f4952fb630c57e3568042f96ec20' 
  AND token = 't5ncBuFvOvExSQnr+DRrrGO9MLLMK29bK7zwh+clDSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}