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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad4273c434343624044977ce6cc58ce0e16d1cefac3e90345b563877eb65c166' 
  AND token = 'eKW9XuxzggH3bq01sSY+cbrW9WH8eMx02Pltb+Z9OEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}