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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b26ebc48d4c4f08f838402d7a2a9842f1dca065eca5368ab35cdfea07217873b' 
  AND token = '/bRSipu4J8zvy9BqsO9adh47RDiL471YwghuWSC68Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}