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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c1dc1e4fe6f6506563fbfb6f74e833bf3bfe8636727cb1ee73edf01de57414' 
  AND token = 'yfTb4tZzN+8j403a3BDWRfc81zaHuayapWfsLhr2Ie4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}