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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d9ff84d745b52ed1ea75490aa52a8af69d84880464dc97cbf6aceed47609631' 
  AND token = 't52quZTT90SswCTP9UnQVq4r4NyCX/FUOUJW30xmIrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}