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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e67837d86eddbe7fd2c24afff70e974c823e32de75a02ea69d3d1aae77582495' 
  AND token = 'rm8I9vZEaRyAa0QORj27Sk28Gp4tPQhVy9T2KF8e6ZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}