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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '682f3278f7b65c6909afa0fa4a89d626a9ada5bf1a33e267029020c32f7e52f4' 
  AND token = 'F0mjpVioQiGx+RslaV5kdXKf5M0CvtAgFE7Z8cy3VjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}