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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44f21c9e6d7e62ff1bbee4412696cd529fa27d1f290232561c1ac336e7bb1f06' 
  AND token = 'imvOCEkW1AiuG674/XV7PhZSL7kLyfq7bx+84s270Ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}