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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da57cb39c5845ea952db62cab1c22157ecfb21a3573b894b251edb0f993250c0' 
  AND token = 'YiGmo0iy+j9O4fgElklxTNtZvnX3AqUfsAWRS/W0aZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}