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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de7f2665fbb5b0bcd4b29d8b06321344a2123c740d4acca1e898220ff2cde52' 
  AND token = 'zYfX1WybNzt6ScDhB4tEVmM23a6XMAxcTfXtPQVKg40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}