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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50aee59db31bf63313bb582dff1aa10332fdf52bcbc51d306183cc17c383f047' 
  AND token = 'wW5fKpijrKPH085e6lHo08+rRcOzps3z0oj1/VFQ06E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}