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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f65e291e977149152361b8b23029c3f010c19def1ba06c4dc3ef8563e65f8528' 
  AND token = 'hudQrmXIdSkkeD9bt+Zb4Qf1FXVA0IkUbMUXvtjqetQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}