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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b14fe65270b34c0979429dc62970eecf5f89f9038c2156e235c419a0cad7601' 
  AND token = 'c4s67eXClfbtuOD9kUcY/odCNwoG5do8KmNejpngnSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}