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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40e04165b5e065a64b7cc24e4f1a298adcf53e13dcea1677e112b967c354451a' 
  AND token = 'LH4V+0xVAyzJPbPPQ84ne4kltU0K8ZTd9WppDRymtS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}