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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce4f72c1467bad30e80cc0200a3325a21396ad86227ba29f48660f9328646f18' 
  AND token = 'LyW+2kQs7rENfagtqlFmxEUbHFscw3KEaUT3p6nXA5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}