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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0781857e056ad646c26c98376e73955699841d1b50441d39e02b202023a34c56' 
  AND token = 'XmYw0RV4bgSQFLELwfxamfmF2gnayH/Te126xdnGb40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}