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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5134d491ac49c5393ff5da2aca597db773fe46b96ae6b2e11cff684b30f21b5a' 
  AND token = 'GY8TrWHz1vE1f4xaYdQy9Xoq6rbVIj6kMydLYgj2hDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}