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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5129f44dba9f32cfe1124134f6c1c0b2371b33985cf5ca329d5c24cf17aeaacd' 
  AND token = 'v3UIdswdJg78KvFd5+DVgF/0DfnW5slZCbTvdnl80R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}