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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14ff4017e349506128998bbe7301dcc373883873c0d231007f7c11fbc495e7cd' 
  AND token = 'uUvSN8nhB5zkazb+KRo2PB3uq0jnA3jxf/3ok0VznY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}