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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57a36c24947e575d7c340fb1fcd7e237ef8ab8e2a267c3d0e82df3fe78072047' 
  AND token = 'v5Lw2Qi9ADWiLLlRm/oF383mqiV/CF/KZfRCSj7nJcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}