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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9973da2d6c99b51531316bb92b289d7f80032c29b59f86956de4e4f2da235aa' 
  AND token = '3iPhQi06DVc+7nCSB2LfGlPaDmX6li7b5LdBpn6XiH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}